If you have problem with ePSXe, then use the guides or search use search, but if the neither fixes the sound issue, then it's your Image file, as for converting, i use Alcohol 120% or Alcohol 52%, both make perfect convertions.
(It doesn't matter about .Cue if you convert it and .BIN into an ISO, an ISO has all the data in it, it is the only file i think which doesn't need to be mounted therefor only needs the data, nothing else, so there you go, a super do everything file)