Do any Emulators support 'rapid fire buttons'

[Pdub247]

Hi all, I used to have a 6button megadrive/genesis controller with rapid fire switches, was great for 'Desert strike'...
Just wondered if any Emulators support rapid fire buttons?

[Mupen64 Man]

I don't see why they shouldn't, the input is being triggered within the controller, so it should translate to inputs in the emulator. Why? Don't have a way of testing it?