The game was designed for Windows 95 so if you have Windows XP Pro, you could try running it in Win 95 compatibility mode (right click the game .exe and select 'properties', then the 'compatibility' tab, then the Win95 compatibility option).
Also bear in mind it might be a game that requires the CD be in the drive for authentication. Ordinarily its easy to find and download a NoCD crack, but for a game that old you might struggle and end up having to run the ISO through a Virtual CD Drive like DaemonTools or Alcohol 120%
If thats no good, you could try getting the 3DO version and running it with the FreeDO emulator.